Understanding Angina Pectoris
Angina pectoris is the medical term for chest pain or discomfort usually due to coronary artery disease (CAD) which often causes a condition called myocardial ischemia. The symptoms of angina are felt when the heart muscle doesn't get as much blood or oxygen as it needs, usually because the arteries have become narrowed or blocked. When this happens, it can cause an uncomfortable pressure, fullness, squeezing, or pain in the center of the chest. Discomfort also may be felt in the neck, jaw, shoulder, back, or arm.1
Other Symptoms
Sometimes angina can be accompanied by shortness of breath, nausea, dizziness, or tiredness. Some people may break into a cold sweat, or feel their heart pounding. The discomfort usually develops gradually, without a sudden sharp pain.
What Triggers Angina?
Typical angina can be triggered by sudden physical activity—like running to catch a bus. It may happen during exercise, or when you are mentally or emotionally stressed.2 Angina can also be triggered by eating rich or heavy meals. Angina can happen several times a day, or only once in a while. It is important to know what pattern of angina is typical for you.
What Causes an Angina Attack?
Stable angina is usually a symptom of coronary artery disease. Coronary artery disease is almost always caused by narrowing of the arteries. This narrowing is also called atherosclerosis [ath-uh-roh-skluh-roh-sis] and it develops when cholesterol and other materials are deposited in the wall of an artery, forming plaques. As the plaques get bigger, they start to block the artery. With time, calcium starts to build up too. This can take many years.2
Who Gets Angina?
CAD is most common among older adults. In the United States, 1 out of 6 people age 65 and over will develop CAD each year. Both men and women can get angina, although men usually develop it about 10 years earlier than women. According to the American Heart Association, over 10 million people in the United States suffer from angina pectoris and there are over 500,000 new cases of angina each year.3
Are You at Risk?
Certain behaviors, circumstances, or disorders—called risk factors—can increase the likelihood of CAD. Some risk factors can be prevented, some are out of our control. The main risk factors are:
- Age
- Family history of parents or siblings who developed CAD before age 50
- Conditions such as high blood pressure, diabetes, and high cholesterol
- Smoking
- Physical inactivity
- Excess weight
If you feel you may be at risk, or have experienced chest pain, discuss your symptoms with your healthcare professional. He or she will be able to advise you.
Indications and Usage:
Nitrolingual Pumpspray is indicated for acute relief of an attack or prophylaxis of angina pectoris due to coronary artery disease.
Ask your healthcare professional if Nitrolingual Pumpspray is right for you.
Effective Pain Relief
- Acute relief of an attack or prophylaxis of angina pectoris due to coronary artery disease
- Increase in exercise tolerance and time to onset of angina
- Well tolerated, with generally mild to moderate side effects
Spray Form
- Consistent dosing with each metered lingual spray
- Available in two convenient bottle sizes: a travel-size 60 metered lingual spray bottle and a 200 metered lingual spray bottle.
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Stability & Potency
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Important Safety Information
Nitrolingual Pumpspray should not be used if you are allergic to nitroglycerin or if you are using medications for erectile dysfunction such as sildenafil, vardenafil, and tadalafil. Using Nitrolingual Pumpspray with these products may cause low blood pressure, known as hypotension, due to widening of blood vessels.
You should use Nitroglycerin with caution in the early days after a heart attack and it may aggravate the angina caused by a condition known as hypertrophic cardiomyopathy. Increased hypotension, mainly when standing upright, may occur even with small doses of nitroglycerin and may result in slow heart beat and increased angina. It should be used with caution if you are dehydrated due to drug therapy or if you have low blood pressure.
You might develop a tolerance to this drug or to other nitrates and nitrites.
Headache is the most reported side-effect and may be severe and persistent. Other side effects that may have been reported are headache, dizziness, or numbness and tingling of the skin.
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Talk to your healthcare provider to see if Nitrolingual is right for you.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088
References:
- American Heart Association. "Symptoms and Diagnosis of Heart Attack". Available at:
http://www.heart.org/HEARTORG/Conditions/HeartAttack/SymptomsDiagnosisofHeartAttack/Symptoms-and-Diagnosis-of-Heart-Attack_UCM_002041_Article.jsp. Accessed February 4, 2011. - Hemingway H, McCallum A, Shipley M, Manderbacka K, Martikainen P, Keskimäki I. Incidence and prognostic implications of stable angina pectoris among women and men. JAMA. 2006;295(12):1404-1411. Accessed June 17, 2011.
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American Heart Association. "Heart Attack and Angina Statistics". Available at:
http://www.americanheart.org/presenter.jhtml?identifier=4591. Accessed February 4, 2011.
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The following trademarks are either registered trademarks or trademarks of Pohl-Boskamp in the United States and/or other countries: Pohl-Boskamp word mark; Pohl-Boskamp logo; Nitrolingual word mark; Peppermint flavor of nitroglycerin; Peppermint scent of nitroglycerin; Nitrolingual Pumpspray shapes; Nitrolingual Pumpspray colors; and the sound of Nitrolingual Pumpspray. Arbor Pharmaceuticals' use of Nitrolingual is under license from G. Pohl-Boskamp GmbH & Co. KG.